Invega Breast Cancer Lawsuit

Invega Lawsuit Update 2025

Women and men diagnosed with breast cancer after taking Invega may qualify for substantial compensation.

Emerging scientific evidence confirms a link between antipsychotic medications like Invega (generic: paliperidone) and elevated breast cancer risk due to prolactin hormone disruption. Pharmaceutical giant Janssen Pharmaceuticals—a Johnson & Johnson subsidiary—faces nationwide lawsuits alleging failure to warn patients and physicians about this life-threatening side effect.

On this page, the Invega breast cancer lawyers at Wisner Baum explain the science behind the antipsychotic lawsuits, eligibility criteria, potential settlement values, and more.

If you developed breast cancer after taking Invega (paliperidone), our law firm can help you. Our Invega lawyers represent clients on a contingency fee basis, which means if we don’t obtain compensation for you in a verdict or settlement, you don’t pay. Fill out our case evaluation form today to begin the claims. 

Invega Lawsuit: Your Guide to Legal Rights & Compensation

What is Invega (Paliperidone)?

Invega (paliperidone) is a pharmaceutical drug used to treat schizophrenia and schizoaffective disorder in adults and adolescents. It balances two key brain chemicals—dopamine and serotonin—to help improve clear thinking and stabilize moods.

Invega has been sold as a daily tablet and an injection.

  • Invega Sustena is an extended-release injection released into the body over one month.
  • Invega Trinza is an extended-release injection released into the body over 3 months.
  • Invega Hafyera is an injection released into the body over 6 months.
  • Invega Erzofri is an extended-release injectable suspension approved by the FDA (July 2024).

Invega Lawsuit Update 2025

August 1, 2025: Invega attorney Monique Alarcon said in a press release issued this week:

"In what has come to be known as 'the Big Pharma Playbook,' antipsychotic drug manufacturers used a deceptive pattern of off-label marketing to increase sales for medications developed to treat extreme psychotic conditions like schizophrenia. 

Because schizophrenia and bipolar disorder affect a small portion of the population, the drug makers sought a bigger market among doctors prescribing the medications to elderly patients with dementia and many others without schizophrenia or bipolar disorder. They were told the potent psychiatric drugs would provide generalized ‘mood stabilization.’

“They did this despite knowing that these conditions can be addressed by other widely available prescription drugs like Abilify (aripiprazole), Clozaril (clozapine), Geodon (ziprasidone), and Seroquel (quetiapine), which are considered safer and more effective.”

Read the press release on our ongoing litigation here.

The Scientific Basis for Invega Breast Cancer Lawsuits

The three primary allegations in the Invega breast cancer lawsuits are:

  1. Exposure to certain antipsychotics, including Invega (paliperidone), can induce hyperprolactinemia (abnormally high levels of the hormone prolactin), which can cause breast cancer.
  2. Janssen Pharmaceuticals, Inc., a subsidiary of Johnson & Johnson, has been aware of the hyperprolactinemia issue since the 1990s but failed to warn of the risk of breast cancer and wrongfully concealed information concerning Invega’s dangers.
  3. Numerous studies have confirmed the risk of developing breast cancer increases with long-term exposure to Invega and its generic form.

Prolactin's Suspected Role in Breast Cancer Development

Researchers do not yet know the precise pathways by which Invega causes cancer. However, Invega belongs to a class of antipsychotics known to dramatically increase prolactin levels. Chronic prolactin elevation creates a tumorigenic environment through three key mechanisms:

  1. Cellular Proliferation: Prolactin activates JAK2-STAT5 signaling pathways that accelerate cell division in mammary tissue.
  2. Apoptosis Suppression: Elevated prolactin weakens natural tumor suppression mechanisms in precancerous lesions.
  3. Receptor Overexpression: According to a Janssen study, “more than 95% of [breast cancer tumors] display overexpression of the prolactin receptor, and genes that are activated by this receptor are associated with tumorigenesis and cancer cell proliferation.”

A landmark 2022 study of over 500,000 U.S. women found:

  • 62% higher breast cancer risk for Category 1 drugs (high prolactin-elevating agents like Invega and Risperdal)
  • 54% increased risk for Category 2 drugs (moderate prolactin effects)
  • No significant risk for Category 3 drugs (low prolactin impact)

Eligibility for Invega Lawsuits

You may be eligible for an Invega lawsuit if you took paliperidone and developed breast cancer. 

The best way to determine whether you qualify to join the Invega breast cancer lawsuit is to consult Wisner Baum’s legal team. Our Invega lawyers offer free and fast case evaluations. The questionnaire takes about five minutes to complete. Once we receive your information, we will review it and promptly respond with the next steps.

What is the Deadline to File an Invega Breast Cancer Lawsuit?

The deadline to file an Invega breast cancer claim can vary depending on where you live, where you were prescribed the drug, and more. We highly recommend starting the legal process by filling out a case evaluation form as soon as possible. This helps ensure you do not miss the applicable legal deadline to file your case.

Potential Compensation in Invega Lawsuits

A breast cancer diagnosis creates profound physical, emotional, and financial consequences. Women who took Invega and later developed breast cancer should not have to face the financial consequences due to a drug maker’s alleged failure to warn.

When dangerous or defective medications harm people, they most commonly join together in a legal action called a mass tort lawsuit. These cases allow individuals to hold drug companies accountable for injuries caused by their products. While mass torts share similarities to class action lawsuits, they differ in that compensation to each plaintiff in a mass tort reflects their personal damages. So even though many people are suing together, each person’s compensation is based on their specific losses.

What Are Economic Damages?

One of the most important parts of these Invega lawsuits is recovering economic damages—money to cover the financial losses caused by the alleged harm. These are out-of-pocket costs and financial losses a person suffers because of their injuries. These are real, measurable expenses—like medical bills or lost wages—that can be proven with receipts, pay stubs, or other documents.

Economic damages may include:

  1. Medical Expenses

The most common out-of-pocket expense is medical costs. This includes all the money spent treating injuries caused by the defective drug. For example:

  • Hospital stays: If you need to stay in the hospital because of side effects from the medication or other treatment.
  • Surgeries or procedures: Costs for operations or treatments required to address health problems caused by the drug.
  • Medications: Prescription drugs needed to manage symptoms or complications.
  • Doctor visits: Bills for appointments with specialists, therapists, or other healthcare providers.
  • Medical equipment: Items like wheelchairs or other devices.

Future medical expenses (like physical therapy or follow-up surgeries) can also be included if your diagnosis requires ongoing care.

  1. Lost Income

Many people miss work—or can’t work at all—because of harm from a defective drug. Lost income may cover:

  • Wages lost while recovering: If you took unpaid leave or used sick days.
  • Reduced earning capacity: If your diagnosis forces you to switch to a lower-paying job or work fewer hours.
  • Future lost income: If your diagnosis prevents you from working long-term.
  1. Transportation Costs

Traveling to medical appointments adds up. Economic damages can include:

  • Gas or public transit fares for trips to hospitals or pharmacies.
  • Parking fees at medical facilities.
  • Ambulance or medical transport bills for emergencies.
  1. Caregiver Costs

A breast cancer diagnosis may require help with daily tasks like bathing, cooking, or taking medications. Economic damages can cover:

  • Professional nursing care at home or in a facility.
  • Family caregiver expenses: If a loved one takes time off work to care for you, their lost wages may be included.

How Are Economic Damages Calculated?

Each person’s economic damages depend on their unique situation. Courts review:

  • Receipts and bills to verify medical costs.
  • Pay stubs or tax returns to prove lost income.
  • Expert testimony to estimate future expenses (like lifelong medical care).

Why Economic Damages Matter

Drug manufacturers have a duty to make safe products. When they fail, economic damages help injured people:

  • Avoid debt from overwhelming medical bills.
  • Stay financially stable while recovering.
  • Rebuild their lives after severe health complications.

By covering these costs, the legal system aims to put injured individuals back in the position they were in before taking the harmful drug.

Punitive Damages

Punitive damages are monetary penalties awarded to the plaintiffs in addition to the compensatory damages listed above. Punitive damages are designed to:

  1. Punish companies that engage in malicious, reckless disregard for safety.
  2. Deter similar harmful conduct in the future.

Why Choose Our Invega Breast Cancer Attorneys

Wisner Baum has won some of the nation’s most highly publicized prescription drug cases. Some of our successes in litigation against Big Pharma include:

  • $105 Million Pharmaceutical Settlement
  • $63 Million Pharmaceutical Class Action Settlement
  • $40 Million Pharmaceutical Class Action Settlement
  • $28 Million Pharmaceutical Class Action Settlement
  • $10 Million Pharmaceutical Class Action Settlement

Our Invega attorneys offer free and confidential case evaluations. We litigate these lawsuits on contingency, which means if we don’t win, you don’t pay. Let us fight for justice and compensation so you can focus on what matters most: healing.

Get Started
Call (310) 207-3233 or fill out the form below and request a free consultation.
20,000+ Families Represented

"Wisner Baum gave exceptional attention to all aspects of the case, detailed inquiry, and tenacious overview of all the information submitted. The paralegals are efficient and diligent. I was completely surprised to find an empathic personal message to take care of my own health during the challenging time of being a full-time caretaker.*"

Mary Flores
Reviewed
on Google
Read More Reviews
Case Results
We Demand Accountability.
More Successful Results
$2.0 Billion Verdict
Personal Injury
In May of 2019, the jury in the case of Pilliod et al. v, Monsanto Company ordered the agrochemical giant to pay $2.055 billion in damages to the plaintiffs, Alva and Alberta Pilliod, a Bay Area couple in their 70s. R. Brent Wisner served as co-lead trial attorney for the Pilliods, delivering the opening and closing statements and cross-examining several of Monsanto’s experts. Wisner Baum managing shareholder, Michael Baum and attorney Pedram Esfandiary also served on the trial team in the Pilliod case. The judge later reduced their award to $87M. Monsanto appealed the Pilliod’s verdict which the California Court of Appeal for the First Appellate District denied on August 9, 2021. Monsanto then requested the California Supreme Court review the appeal’s court decision, which the court denied on Nov. 17, 2021. Monsanto (Bayer) then submitted a petition for a writ of certiorari with the U.S. Supreme Court which SCOTUS denied on June 27, 2022, allowing the final judgment of $87M to remain intact.
In May of 2019, the jury in the case of Pilliod et al. v, Monsanto Company ordered the agrochemical giant to pay $2.055 billion in damages to the plaintiffs, Alva and Alberta Pilliod, a Bay Area couple in their 70s. R. Brent Wisner served as co-lead trial attorney for the Pilliods, delivering the opening and closing statements and cross-examining several of Monsanto’s experts. Wisner Baum managing shareholder, Michael Baum and attorney Pedram Esfandiary also served on the trial team in the Pilliod case. The judge later reduced their award to $87M. Monsanto appealed the Pilliod’s verdict which the California Court of Appeal for the First Appellate District denied on August 9, 2021. Monsanto then requested the California Supreme Court review the appeal’s court decision, which the court denied on Nov. 17, 2021. Monsanto (Bayer) then submitted a petition for a writ of certiorari with the U.S. Supreme Court which SCOTUS denied on June 27, 2022, allowing the final judgment of $87M to remain intact.
Continue Reading
$2.0 Billion Verdict
Personal Injury

In May of 2019, the jury in the case of Pilliod et al. v, Monsanto Company ordered the agrochemical giant to pay $2.055 billion in damages to the plaintiffs, Alva and Alberta Pilliod, a Bay Area couple in their 70s. R. Brent Wisner served as co-lead trial attorney for the Pilliods, delivering the opening and closing statements and cross-examining several of Monsanto’s experts. Wisner Baum managing shareholder, Michael Baum and attorney Pedram Esfandiary also served on the trial team in the Pilliod case.

The judge later reduced their award to $87M. Monsanto appealed the Pilliod’s verdict which the California Court of Appeal for the First Appellate District denied on August 9, 2021. Monsanto then requested the California Supreme Court review the appeal’s court decision, which the court denied on Nov. 17, 2021. Monsanto (Bayer) then submitted a petition for a writ of certiorari with the U.S. Supreme Court which SCOTUS denied on June 27, 2022, allowing the final judgment of $87M to remain intact.

$289.2 Million Verdict
Personal Injury
$289.2 million jury verdict in Monsanto Roundup trial Wisner Baum co-represented Dewayne “Lee” Johnson in the first Roundup cancer lawsuit to proceed to trial. On Aug. 10, 2018, a San Francisco jury ordered Monsanto to pay $39.25 million in compensatory damages and $250 million in punitive damages to Mr. Johnson, a former groundskeeper who alleged exposure to Monsanto’s herbicides caused him to develop terminal non-Hodgkin lymphoma. Months after the jury verdict, the judge overseeing the trial reduced the punitive damages to $39.25 million. Mr. Johnson decided to accept the remittitur, bringing the adjusted amount awarded to Mr. Johnson $78.5 million. Monsanto (Bayer) appealed the verdict and Johnson cross appealed. On July 20, 2020, the First Circuit Court of Appeals upheld the verdict against Monsanto but reduced Mr. Johnson’s award to $20.5 million. The company chose not to take the case to the U.S. Supreme Court, ending the litigation.
$289.2 million jury verdict in Monsanto Roundup trial Wisner Baum co-represented Dewayne “Lee” Johnson in the first Roundup cancer lawsuit to proceed to trial. On Aug. 10, 2018, a San Francisco jury ordered Monsanto to pay $39.25 million in compensatory damages and $250 million in punitive damages to Mr. Johnson, a former groundskeeper who alleged exposure to Monsanto’s herbicides caused him to develop terminal non-Hodgkin lymphoma. Months after the jury verdict, the judge overseeing the trial reduced the punitive damages to $39.25 million. Mr. Johnson decided to accept the remittitur, bringing the adjusted amount awarded to Mr. Johnson $78.5 million. Monsanto (Bayer) appealed the verdict and Johnson cross appealed. On July 20, 2020, the First Circuit Court of Appeals upheld the verdict against Monsanto but reduced Mr. Johnson’s award to $20.5 million. The company chose not to take the case to the U.S. Supreme Court, ending the litigation.
Continue Reading
$289.2 Million Verdict
Personal Injury

$289.2 million jury verdict in Monsanto Roundup trial

Wisner Baum co-represented Dewayne “Lee” Johnson in the first Roundup cancer lawsuit to proceed to trial. On Aug. 10, 2018, a San Francisco jury ordered Monsanto to pay $39.25 million in compensatory damages and $250 million in punitive damages to Mr. Johnson, a former groundskeeper who alleged exposure to Monsanto’s herbicides caused him to develop terminal non-Hodgkin lymphoma.

Months after the jury verdict, the judge overseeing the trial reduced the punitive damages to $39.25 million. Mr. Johnson decided to accept the remittitur, bringing the adjusted amount awarded to Mr. Johnson $78.5 million.

Monsanto (Bayer) appealed the verdict and Johnson cross appealed. On July 20, 2020, the First Circuit Court of Appeals upheld the verdict against Monsanto but reduced Mr. Johnson’s award to $20.5 million. The company chose not to take the case to the U.S. Supreme Court, ending the litigation.

$265 Million Settlement
Fatal Train Crash
In 2016, Wisner Baum attorney Timothy A. Loranger and six other attorneys in the Plaintiffs’ Management Committee were able to secure a $265 million settlement for victims of the 2015 Amtrak 188 derailment in Philadelphia, one of the largest in the U.S. for 2016.
In 2016, Wisner Baum attorney Timothy A. Loranger and six other attorneys in the Plaintiffs’ Management Committee were able to secure a $265 million settlement for victims of the 2015 Amtrak 188 derailment in Philadelphia, one of the largest in the U.S. for 2016.
Continue Reading
$265 Million Settlement
Fatal Train Crash

In 2016, Wisner Baum attorney Timothy A. Loranger and six other attorneys in the Plaintiffs’ Management Committee were able to secure a $265 million settlement for victims of the 2015 Amtrak 188 derailment in Philadelphia, one of the largest in the U.S. for 2016.

When companies choose profit over people, we fight. Wisner Baum exposes injustice, demands accountability, and delivers real results for real people. Your Path to Justice Starts Here.
Los Angeles
11111 Santa Monica
Blvd Suite 1750
Los Angeles, CA 90025
Get Directions
Bay Area
100 Drakes Landing Road
Suite 160
Greenbrae, CA 9490412
Get Directions
Washington, D.C.
2101 L St NW 

Suite 800
Washington, DC 20037
Get Directions
Los Angeles
11111 Santa Monica
Blvd Suite 1750
Los Angeles, CA 90025
Get Directions
Bay Area
100 Drakes Landing Road
Suite 160
Greenbrae, CA 9490412
Get Directions
Washington, D.C.
2101 L St NW 

Suite 800
Washington, DC 20037
Get Directions
The information on this website is for general information purposes only. Nothing on this site should be taken as advice for any individual case or situation. This information is not intended to create, and receipt or viewing does not constitute a client relationship.
Send Us Your Case Details
We’ll respond and let you know the best way to proceed with your case.
crossarrow-up linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram